PUBLICAÇÕES CIENTÍFICAS DO LABORATÓRIO DE NEUROFISIOLOGIA

2013

• Sleep disturbances in Parkinson’s disease: the contribution of dopamine in REM sleep regulation
• REM sleep deprivation generates cognitive and neurochemical disruptions in the intranigral rotenone model of Parkinson’s disease

2014

• Dopaminergic D2 receptor is a key player in the substantia nigra pars compacta neuronal activation mediated by REM sleep deprivation
• REM Sleep Deprivation Reverses Neurochemical and Other Depressive-Like Alterations Induced by Olfactory Bulbectomy
• Does Parkinson’s Disease and Type-2 Diabetes Mellitus Present Common Pathophysiological Mechanisms and Treatments?
• Putative role of monoamines in the antidepressant-like mechanism induced by striatal MT2 blockade
• Olfactory impairment in the rotenone model of Parkinson’s disease is associated with bulbar dopaminergic D2 activity after REM sleep deprivation 
• Ascending nociceptive control contributes to the antinociceptive effect of acupuncture in a rat model of acute pain

2015

• Stretch, Shrink, and Shatter the Rhythms: The Intrinsic Circadian Period in Mania and Depression
• Social interaction with rat exposed to constant light during lactation prevents depressive-like behavior induced by constant light in adulthood

2016

• REM sleep deprivation promotes a dopaminergic influence in the striatal MT2 anxiolytic-like effects
• Unraveling a new circuit for sleep regulation in Parkinson’s disease
• Cholinergic Oculomotor Nucleus Activity Is Induced by REM Sleep Deprivation Negatively Impacting on Cognition. Molecular Neurobiology

2017

• Olfactory impairment is related to REM sleep deprivation in rotenone model of Parkinson’s disease
• A circuitry for sleep in Parkinson’s disease
• Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3-/- mice, but not wildtype mice

2018

• REM sleep deprivation and dopaminergic D2 receptors modulation increase recognition memory in an animal model of Parkinson’s disease
• Nucleus accumbens mediates the pronociceptive effect of sleep deprivation the role of adenosine A_2A and dopamine D₂ receptors (Coment for Giancarlo Vanini: Nucleus accumbens a novel forebrain mechanism underlying the increase in pain sensitivity caused by rapid eye movement sleep deprivation)
• Pronociceptive effects mediated by adenosinergic A_2A activity at the nucleus accumbens, but what about the autonomic nervous system? (Reply: journals.lww.com/pain/Citation/2018/05000/Reply.22.aspx)
• Chronic sleep restriction increases pain sensitivity over time in a periaqueductal gray and nucleus accumbens dependent manner
• Dopaminergic mechanisms in periaqueductal gray-mediated antinociception
• Pain Inhibits Pain: an Ascending-Descending Pain Modulation Pathway Linking Mesolimbic and Classical Descending Mechanisms

2019

• Chronic sleep restriction in the rotenone Parkinson’s disease model in rats reveals peripheral early-phase biomarkers